Diazaborines and drug compositions
US4199573A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 27, 1978 |
| Grant date | Apr 22, 1980 |
| Priority date | — |
| Expiry date | Jul 27, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/025
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Derivative of 1-hydroxy-benzo-2,3,1-diazaborines which are substituted in the 2-position by a sulfo group linked to a defined aliphatic radical like alkyl or alkenyl and which may be substituted on the benzene ring by one or more lower alkyl radicals and/or halogen atoms and salts of such compounds. The pharmaceutical compositions containing these diazaborines are highly effective against gram-negative bacteria. The new compounds are prepared by reacting o-formyl phenyl boric acid, which may be substituted, with the respective aliphatic sulfonic acid hydrazide or by reacting the respective (substituted) benzaldehyde sulfonylhydrazone with a boron trihalogenide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.