Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4199574A · kind A · utility
136Cited by
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81Claims
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Assignee
Inventor
Key dates
| Filing date | Mar 1, 1976 |
| Grant date | Apr 22, 1980 |
| Priority date | — |
| Expiry date | Mar 1, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
9-Hydroxyethoxymethyl (and related) derivatives of certain 6-, and 2,6-substituted purines have been discovered to have potent anti-viral activities. Novel compounds and their pharmaceutically acceptable salts, pharmaceutical formulation containing the compounds of this invention, and the treatment of viral infections with these formulations are all disclosed. 9-(2-hydroxyethoxymethyl) guanine and 2-amino-9-(2-hydroxyethoxymethyl)adenine are examples of especially active compounds of this invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.