6-Phenyl-4H-s-triazolo-[3,4c]-thieno-[2,3e]-1,4-diazepines and salts thereof

US4199588A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Karl-Heinz Weber · Gau-Algesheim, DE
• Adolf Bauer · Olching, DE
• Peter Danneberg
• Franz J. Kuhn · Gau-Algesheim, DE

Key dates

• Filing date: Nov 30, 1977
• Grant date: Apr 22, 1980
• Expiry date: Nov 30, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, chlorine, bromine or alkyl of 1 to 4 carbon atoms; PA1 R.sub.2 is hydrogen, fluorine, chlorine, bromine, nitro or trifluoromethyl; and PA1 R.sub.3 is chlorine, bromine, alkoxy of 1 to 3 carbon atoms, alkylmercapto of 1 to 3 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, cycloalkenyl of 3 to 6 carbon atoms, or a saturated or unsaturated 5- to 6-membered heterocycle comprising an oxygen, sulfur or nitrogen heteroatom, where a substitutable nitrogen heteroatom may optionally have a lower akyl substituent attached thereto; and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as tranquilizers, muscle-relaxants and anticonvulsants.