Determination of glycosylated hemoglobin in blood
US4200435A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 26, 1978 |
| Grant date | Apr 29, 1980 |
| Priority date | — |
| Expiry date | Dec 26, 1998 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH04M19/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for determining glycosylated hemoglobin in blood samples which involves liberating hemoglobins from red blood cells by chemical or physical means and reacting non-glycosylated hemoglobin with an allosteric site binding substance which reacts with the allosteric binding site of non-glycosylated hemoglobin and thereby alters the distribution between allosteric forms of the hemoglobins and measuring the change. This method is useful in monitoring glucose metabolism for detecting and controlling diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.