Patent · US Expired

Determination of glycosylated hemoglobin in blood

US4200435A · kind A · utility

23Cited by
5References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 26, 1978
Grant dateApr 29, 1980
Priority date
Expiry dateDec 26, 1998

Classification

  • Technology area (CPC H)Electricity
  • CPC primaryH04M19/04
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method for determining glycosylated hemoglobin in blood samples which involves liberating hemoglobins from red blood cells by chemical or physical means and reacting non-glycosylated hemoglobin with an allosteric site binding substance which reacts with the allosteric binding site of non-glycosylated hemoglobin and thereby alters the distribution between allosteric forms of the hemoglobins and measuring the change. This method is useful in monitoring glucose metabolism for detecting and controlling diabetes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.