Patent · US Expired

Preparation of .alpha.-hydroxy-.beta.,.beta.-dimethyl-.gamma.-butyrolactone

US4200582A · kind A · utility

2Cited by

4References

1Claims

0Family size

Assignee

BASF SE

Inventors

Harry Distler · Worms, DE
Walter Goetze · Schifferstadt, DE

Key dates

Filing date	Dec 15, 1978
Grant date	Apr 29, 1980
Priority date	—
Expiry date	Dec 15, 1998

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D307/33
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A process for the preparation of .alpha.-hydroxy-.beta.,.beta.-dimethyl-.gamma.-butyrolactone (pantolactone) by condensation of formaldehyde with isobutyraldehyde to give hydroxypivalaldehyde, conversion of the latter to its cyanohydrin, and subsequent acid hydrolysis and lactonization, wherein formaldehyde and butyraldehyde are reacted in the presence of a tertiary amine, hydrocyanic acid, at a concentration not exceeding 1% by weight in the reaction mixture, is used to form the cyanohydrin, and the hydrolysis and simultaneous lactonization are carried out with gaseous hydrogen chloride.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.