3-Amino-17a-aza-D-homoandrostane compounds, and pharmaceutical compositions containing them
US4200636A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 17, 1978 |
| Grant date | Apr 29, 1980 |
| Priority date | — |
| Expiry date | Aug 17, 1998 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA63H1/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new 3-amino-17a-aza-D-homo-5.alpha.-androstane derivatives of the general formula I ##STR1## wherein R.sub.1 represents a methylene or an >N--CH.sub.3 group, and n stands for 1 or 2, and the acid addition salts and the quaternary salts of the general formula ##STR2## thereof, wherein R.sub.2 stands for an alkyl or alkenyl group having from 1 to 4 carbon atoms, and A represents a halogen atom, provided that if R.sub.1 stands for an >N--CH.sub.3 group, R.sub.2 is attached to the nitrogen of that >N--CH.sub.3 group. The new compound possess a non-polarizing neuromuscular blocking activity and have a short activity period.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.