Monoradioiodinated derivatives and precursors for production thereon
US4202874A · kind A · utility
6Cited by
4References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 10, 1978 |
| Grant date | May 13, 1980 |
| Priority date | — |
| Expiry date | Mar 10, 1998 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/817
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Monoradioiodinated derivatives of compounds employed in a radioassay prepared from precursors which are either active esters, amino acids, or amines, including a phenolic or imidazole substituent group in which one of the possible two sites on the group for radioiodination is substituted to permit production of a monoradioiodinated derivative. A preferred precursor is an active ester of 3-fluoro-5-radioiodotyrosine which can be coupled to a compound including an amino group to produce a monoradioiodinated derivative of the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.