6'N-Alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B
US4205070A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 21, 1977 |
| Grant date | May 27, 1980 |
| Priority date | — |
| Expiry date | Dec 21, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/224
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel fortimicin antibiotics represented by the formula ##STR1## wherein R.sub.1 is loweralkyl, R.sub.2 is hydrogen or loweralkyl and R.sub.3 is selected from the group consisting of hydrogen, acyl, hydroxyacyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl or an aminoacid residue, loweralkyl, hydroxyloweralkyl, aminoloweralkyl, N-monoloweralkylaminoloweralkyl, N,N-diloweralkylaminoloweralkyl or hydroxy-substituted aminoloweralkyl; and the pharmaceutically acceptable salts thereof, intermediates useful in their preparation, compositions employing the compounds and methods of using the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.