Dithienylalkylamines and process for their production

US4206213A · kind A · utility

Assignee

• Deutsche Gold- und Silber-Scheideanstalt Vormals Roessler

Inventors

• Axel Kleeman · Hanau, DE
• Ingomar Nubert · Offenbach, DE
• Fritz Stroman · Offenbach, DE
• Klaus Thiemer · Hanau, DE

Key dates

• Filing date: Jan 5, 1978
• Grant date: Jun 3, 1980
• Expiry date: Jan 5, 1998

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D333/16
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are prepared compounds of the formula ##STR1## where >A--B-- has either the structure >C(OH)--CH.sub.2 -- or the structure >C.dbd.CH, Alk is a straight or branched chain C.sub.1 -C.sub.5 - alkylene group and -NHY is ##STR2## where R' is hydrogen, phenyl, phenyl substituted once or twice by C.sub.1 -C.sub.4 -alkyl groups, a C.sub.1 -C.sub.4 -alkoxy group or by halogen atoms, a C.sub.1 -C.sub.6 -alkyl group, a C.sub.1 -C.sub.4 -hydroxyalkyl group or a phenalkyl group whose alkyl portion consists of 1-4 carbon atoms or such a phenalkyl group containing 1 to 3 C.sub.1 -C.sub.4 -alkoxy group substituents. The compounds are effective in improving peripheral and cerebral circulation. There are also produced intermediate compounds of formula (II) where NHY is replaced by chlorine, bromine or iodine.