2-Naphthyl acetic acid derivatives and compositions and methods thereof
US4207241A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 27, 1978 |
| Grant date | Jun 10, 1980 |
| Priority date | — |
| Expiry date | Mar 27, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, antipyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.