Patent · US Expired

2,9-Dioxatricyclo[4,3,1,0.sup.3,7 ]decane derivatives and pharmaceutical compositions thereof

US4207331A · kind A · utility

1Cited by

0References

10Claims

0Family size

Assignee

Kali-Chemie Pharma GmbH · DE

Inventors

Peter W. Thies · Hannover, DE
Akiji Asai · Wennigsen (Deister), DE
Samuel David · Dorval, CA

Key dates

Filing date	May 11, 1978
Grant date	Jun 10, 1980
Priority date	—
Expiry date	May 11, 1998

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D493/08
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

New 2,9-dioxatricyclo[4,3,1,0.sup.3,7 ] decane derivatives are disclosed which are substituted by an amino methyl group in the C.sub.3 position, and which exhibit sedative, especially sleep improving properties, and which have the formula ##STR1## wherein R.sub.1 represents an amino group one of R.sub.2 and R.sub.3 is hydrogen and the other represents hydroxy acyloxy or carbamyloxy or R.sub.2 and R.sub.3 jointly represent oxygen one of R.sub.4 and R.sub.5 is hydrogen and the other represents alkyloxy or aralkyloxy y and y' each represent hydrogen or jointly form a bond and their pharmacologically acceptable salts, as well as pharmaceutical formulations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.