Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid

US4207341A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Manfred Hubner · Ludwigshafen am Rhein, DE
• Hans-Frieder Kuhnle · Weinheim, DE
• Ernst-Christian Witte · Mannheim, DE
• Ruth Heerdt · Mannheim, DE
• Rudi Weyer · Kelkheim, DE
• Volker Hitzel · Hofheim, DE

Key dates

• Filing date: Jul 1, 1976
• Grant date: Jun 10, 1980
• Expiry date: Jul 1, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D333/38
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Phenylacetic acid derivatives of the formula ##STR1## wherein A is an aryl radical optionally substituted by halogen, trifluoromethyl, alkyl, alkoxy, alkenyloxy, alkoxyalkoxy, alkyl-substituted amino or aryloxy, or a heterocyclic ring system optionally substituted by halogen, alkyl or alkoxy, PA1 Y is a valency bond or an optionally branched alkylene radical containing up to 3 carbon atoms, and PA1 R.sub.1 and R.sub.2 each independently is hydrogen or a lower alkyl radical, or a physiologically compatible salt or ester thereof, exhibit marked hypoglycaemic and hypolipidaemic activity.