Patent · US Expired

Anti-depressant indole derivatives

US4209521A · kind A · utility

8Cited by
2References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 8, 1978
Grant dateJun 24, 1980
Priority date
Expiry dateNov 8, 1998

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/26
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention concerns a compound of formula II ##STR1## or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof wherein R.sup.5 represents hydrogen, hydroxy, lower alkoxy or lower alkyl, R.sup.6 represents hydrogen or lower alkyl, and R.sup.7 represents phenyl, lower alkoxy phenyl, halophenyl, or thenyl and X represents oxygen or sulphur. These indole derivatives exhibit psychotropic activity. The invention includes a method of alleviating depression in a warm blooded animal afflicted with depression which method comprises administering to said animal an effective amount of a compound of formula II or a pharmaceutically acceptable acid addition salt thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.