Substituted 7-phenyl-2,3-dihydro-imidazo[1,2-.alpha.]imidazoles and salts thereof

US4210659A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Helmut Stahle
• Herbert Koppe · Ingelheim am Rhein, DE
• Werner Kummer · Ingelheim am Rhein, DE
• Walter Kobinger · Wien, AT
• Christian Lillie · Wien, AT
• Ludwig Pichler · Wien, AT

Key dates

• Filing date: Jun 27, 1979
• Grant date: Jul 1, 1980
• Expiry date: Jun 27, 1999

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, methyl, methoxy or trifluoromethyl, provided that one of them is other than hydrogen; and PA1 R.sub.4 and R.sub.5, which may be identical to or different from each other, are each hydrogen or methyl; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.