Patent · US Expired

Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines

US4210749A · kind A · utility

54Cited by
5References
2Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMay 21, 1979
Grant dateJul 1, 1980
Priority date—
Expiry dateMay 21, 1999

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C51/56
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the general formula: ##STR1## and pharmaceutical acceptable salts thereof wherein R is H, lower alkyl, lower alkenyl, lower aralkenyl, cycloalkyl-alkyl, propargyl, lower aralkyl, hydroxyalkyl and esters thereof, heterocyclic, heterocyclic-alkyl, alkyl-aminoalkyl, adamantylalkyl, aralkyl-heterocyclic-alkyl and alkyl-aralkyl-heterocyclic alkyl; PA1 R.sup.1 is H, lower alkyl, phenyl, or phenylloweralkyl; PA1 R.sup.2 is hydrogen or lower alkyl; PA1 R.sup.3 is hydrogen; lower alkoxy; lower alkoxy alkyl ether of hydroxy; amino; lower alkyl; halogen; nitro; hydroxy; or carboxylic acid ester of hydroxy group, useful as analgesics and narcotic antagonists.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.