Patent · US Expired

Compounds

US4211788A · kind A · utility

0Cited by
2References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 11, 1978
Grant dateJul 8, 1980
Priority date
Expiry dateMay 11, 1998

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/94
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There are described compounds of formula I, ##STR1## in which E is a --COOH, a 5-tetrazolyl or an (N-tetrazol-5-yl) carboxamido group, PA1 R.sub.3 is hydrogen or alkyl, PA1 an adjacent pair of W, X, Y and Z form a 5 membered chain comprising alkylene groups and optionally one or two oxygen atoms, the chain optionally being substituted by one or two alkyl groups, PA1 the remaining substituents W, X, Y or Z are hydrogen; halogen; alkyl optionally substituted by one or more of the groups hydroxy, halogen, carbonyl oxygen, phenyl, or alkoxy; alkenyl optionally substituted by phenyl; hydroxy; alkoxy; alkanoyloxy; alkenyloxy; nitro; --NR.sub.1 R.sub.2 or hydroxyalkoxy, PA1 R.sub.1 and R.sub.2, which may be the same or different, are each hydrogen or alkyl, PA1 and pharmaceutically acceptable derivatives thereof. There are also described processes for making the compounds and pharmaceutical, e.g. anti-allergic, compositions containing the compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.