Conversion of stereoisomer into its diastereoisomer
US4213916A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1978 |
| Grant date | Jul 22, 1980 |
| Priority date | — |
| Expiry date | Jun 9, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the conversion of a stereoisomer into its diastereoisomer of a compound having the following general formula: ##STR1## (wherein the asterisk denotes an asymmetric carbon atom; each X is individually hydrogen, alkyl, aryl, alkaryl, aralkyl, alkoxy, aryloxy, halogen, nitro, hydroxy or cyano; R is an organic residue containing one or more centers of asymmetry; and n is 1 to 5), which comprises subjecting the said stereoisomer to the action of an alkali metal carbonate and an inert polar solvent at a temperature in the range 20.degree. to 100.degree. C. and physically separating the required diastereoisomer from the resulting mixture of diastereoisomers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.