Somatostatin analogues
US4215039A · kind A · utility
7Cited by
3References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 15, 1979 |
| Grant date | Jul 29, 1980 |
| Priority date | — |
| Expiry date | Feb 15, 1999 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
##STR1## the linear precursor intermediates therefor or non-toxic acid addition salts thereof in which X.sub.2 is H, NH.sub.2, Ala--Gly--, Ala--D--Ala--, Gly--Gly--Gly--, lower alkanoyl or benzoyl; PA1 X.sub.4 is Arg, His or Lys; PA1 X.sub.5 is His, Tyr or Glu; PA1 X.sub.8 is Trp or D-Trp; PA1 X.sub.10 is Val, .alpha.-Abu, Leu, Phe or Tyr; and PA1 X.sub.14 is Cys, D-Cys or --NH(CH.sub.2).sub.2 --S--, inhibit the release of growth hormone and glucagon without substantial decrease in insulin and are useful in the treatment of acromegaly and diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.