Patent · US Expired

Bio-selective electrode probes using tissue slices

US4216065A · kind A · utility

12Cited by
5References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 18, 1979
Grant dateAug 5, 1980
Priority date
Expiry dateJun 18, 1999

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N27/304
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A bio-selective potentiometric electrode probe for the determination of amino acid concentrations in aqueous liquids comprising an ammonia gas analytical electrode provided at its tip with a closely adjacent thin layer of a fresh animal tissue containing, as a natural constituent thereof, an enzyme effective to catalyze degradation of the specific amino acid in analysis to either ammonia or to an intermediate compound subject to further degradation to ammonia by an additional enzyme, which ammonia is a function of the amino acid concentration in the liquid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.