Phenylethanolamine derivatives
US4217305A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 27, 1978 |
| Grant date | Aug 12, 1980 |
| Priority date | — |
| Expiry date | Sep 27, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D319/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel phenylethanolamine derivatives represented by the formula ##STR1## wherein R represents a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, an amino group, a lower acylamino group, a lower alkylsulfonyl group, or a lower alkylsulfonylamino group; R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be the same or different, each represents hydrogen or a lower alkyl group; R.sub.5 represents an aryl group which may have a substituent, a benzodioxane ring group which may have a substituent, an aryloxy group which may have a substituent, or an arylthio group which may have a substituent; said R.sub.5 being, however, a benzodioxane ring group which may have a substituent, an aryloxy group which may have a substituent, or an arylthio group which may have a substituent when R is a hydroxyl group; and n represents 0 or an integer of 1-3 and the acid addition salts thereof. The compounds of this invention exhibit .alpha.- and .beta.-adrenergic blocking actions and are useful as antihypertensive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.