Substituted steroid-spiro-oxazolidinone derivatives and a process for the preparation thereof
US4218446A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 29, 1979 |
| Grant date | Aug 19, 1980 |
| Priority date | — |
| Expiry date | Mar 29, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P5/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Diuretic pharmaceutically active steroid-spiro-oxazolidinone compounds of the formula (I), ##STR1## wherein R.sup.1 is hydrogen or methyl, PA1 R.sup.2 is C.sub.1-4 alkyl, PA1 R.sup.3 is hydrogen, C.sub.1-4 alkyl or C.sub.2-4 alkenyl, PA1 Z.sup.1 and Z.sup.2 each are hydrogen or together form a second valence bond, or Z.sup.1 is hydrogen and Z.sup.2 is R.sup.4 --S--, PA1 Z.sup.3 and Z.sup.4 each are hydrogen or together form a second valence bond, or Z.sup.3 is hydrogen and Z.sup.4 is R.sup.4 --S--, with at least one of the pairs Z.sup.1 -Z.sup.2 and Z.sup.3 -Z.sup.4 representing hydrogen and an R.sup.4 --S-- group, and PA1 R.sup.4 is hydrogen or alkyl, alkenyl, aralkyl or acyl with up to 7 carbon atoms, provided that when Z.sup.1 and Z.sup.2 together form a valence bond, or Z.sup.1 represents a hydrogen atom and Z.sup.2 and R.sup.4 --S-- group then R.sup.1 is methyl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.