1-(4-Fluorophenyl)-4-[1,2,3,6-tetrahydro -4-(phenylthio)-1-pyridinyl]-butanones and related sulfoxides and sulfones
US4218455A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 10, 1978 |
| Grant date | Aug 19, 1980 |
| Priority date | — |
| Expiry date | Jul 10, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/72
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Tetrahydropyridylbutyrophenones of the following formula IX: ##STR1## wherein x is hydrogen, halogen such as fluorine, chlorine, bromine or iodine, trifluoromethyl, alkoxy, nitro, cyano, amino, lower alkyl of 1 to 6 carbons, aryl or substituted aryl; y is hydrogen or halogen; and n is 0, 1 or 2; and the non-toxic, pharmaceutically acceptable acid addition salts thereof. Tetrahydropyridylbutanols having the formula X: ##STR2## wherein x and y are as defined above, as well as their non-toxic, pharmaceutically acceptable acid addition salts, are also disclosed. The compounds of the invention having the formulas IX and X are useful as antipsychotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.