Process for the preparation of cephamycin antibiotics
US4218563A · kind A · utility
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2References
4Claims
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Key dates
| Filing date | Mar 30, 1979 |
| Grant date | Aug 19, 1980 |
| Priority date | — |
| Expiry date | Mar 30, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An improved process for preparing the antibiotic compound 7.beta.-(2-thienylacetamido)-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-car boxylic acid, from the N-blocked esters of the compound 7.beta.-(D-5-amino-5-carboxyvaleramido)-3-carbamoyloxymethyl-7-methoxy-3-c ephem-4-carboxylic acid (Cephamycin C), by conducting the transacylation of the latter in a homogenous solution containing N-trimethylsilyl loweralkyl carbamates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.