Patent · US Expired

Diagnostic agent and method for the detection of occult blood in feces

US4219336A · kind A · utility

19Cited by

3References

5Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Werner Guthlein · Mannheim, DE
Hans Wielinger · Weinheim, DE
Walter Rittersdorf · Mannheim, DE
Wolfgang Werner · Hersbruck, DE

Key dates

Filing date	Mar 31, 1978
Grant date	Aug 26, 1980
Priority date	—
Expiry date	Mar 31, 1998

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S436/904
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A diagnostic agent for the detection of occult blood in feces comprising hydrogen peroxide and, as a chromogen, guaiaconic acid A, optionally with a stabilizer. The invention provides, as a novel substance, guaiaconic acid A having a specific extinction E.sub.1 cm.sup.1% at 600 nm of at least 200, determined by the reaction with peroxidase and hydrogen peroxide, having infra-red bands at PA1 1600 cm.sup.-1 (m); 1505 cm.sup.-1 (v.s.); PA1 1260 cm.sup.-1 (s;b); PA1 1115 cm.sup.-1 (m); PA1 1025 cm.sup.-1 (m); and PA1 1200 cm.sup.-1 (s;b) and having an R.sub.F value of 0.45 (toluene/dioxan/glacial acetic acid; 90:25:10 v/v/v).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.