Synthesis of substituted phenylacetic acid
US4220592A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 10, 1978 |
| Grant date | Sep 2, 1980 |
| Priority date | — |
| Expiry date | Jul 10, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C51/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A substituted acetonitrile such as .alpha.-isopropyl-p-chlorophenylacetonitrile is hydrolyzed using an acid to produce the corresponding substituted phenylacetic acid such as .alpha.-isopropyl-p-chlorophenylacetic acid in such a manner that, in a lot in any one hydrolysis reaction, (1) the hydrolysis is carried out in at least two steps, (2) an acid to be used in a subsequent first reaction step is a waste acid produced in a previous second reaction step and the subsequent reaction step(s) thereof if any, and (3) an acid to be used in a second reaction step and the subsequent reaction step(s) if any, is the waste acid produced in a previous second reaction step and subsequent reaction step(s), respectively, and a fresh acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.