Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4220637A · kind A · utility
9Cited by
2References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 15, 1977 |
| Grant date | Sep 2, 1980 |
| Priority date | — |
| Expiry date | Jul 15, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K9/005
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates more particularly to the diamide of the 2-(2-acetamido-2-deoxy-3-O-D-glucopyranosyl)-D-propionyl-L-alanyl-D-glutam ic acid, to the pharmaceutical compositions containing said compound in association with a pharmaceutical vehicle. Of particular interest are the oil-free compositions containing said compound, particularly the oil-free aqueous sterile isotonic injectable solutions. These compositions are useful as adjuvants for enhancing the immune response to vaccinant antigens, particularly weak immunogens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.