Basic zirconium complexes and methods of making and using in antiperspirants
US4223010A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 8, 1979 |
| Grant date | Sep 16, 1980 |
| Priority date | — |
| Expiry date | Jan 8, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Basic zirconium gels may be used to form complexes with conventional aluminum and/or zirconium antiperspirant systems. The freshly prepared basic zirconium gels provide both a buffer for the highly acidic aluminum-zirconium complexes and an additional source of zirconium as an active ingredient in the antiperspirant. The preferred basic zirconium gels are basic zirconium-amino acid compounds, particularly basic zirconium glycinates, and the compounds are preferably added to aluminum-zirconium systems in the form of a wet gel. The preferred basic zirconium glycinate is formed by first reacting sodium carbonate with glycine, and then reacting the resulting sodium glycinate with a zirconium oxy or zirconium hydroxy compound to precipitate out the zirconium basic glycinate gel. Zirconium basic carbonates, prepared by reacting sodium carbonate with a zirconium oxy or hydroxy salt, are useful in preparing antiperspirant complexes with lower basic aluminum chlorides (e.g. 1/3 or 2/3 basic), as well as the highly acidic aluminum chloride. Buffers such as urea, amino acids, salts of amino acids, magnesium carbonate, etc. may also be included in the complexes to maintain a pH of at least abo…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.