Urea derivatives to treat anxiety and aggressivity
US4223041A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 25, 1977 |
| Grant date | Sep 16, 1980 |
| Priority date | — |
| Expiry date | Oct 25, 1997 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C275/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Urea derivatives of the formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which are the same or different, each represent a straight- or branched-chain alkyl, alkenyl or alkynyl radical having from 1 to 5 carbon atoms, R.sub.4 and R.sub.5, which are the same or different, each represent a hydrogen atom or a straight- or branched-chain alkyl, alkenyl or alkynyl radical having from 1 to 5 carbon atoms, R.sub.1, R.sub.2 and R.sub.3 being such that: PA0 (a) only one of these radicals can represent an alkenyl or alkynyl group having an unsaturated bond in the .alpha.,.beta.-position with respect to the methylurea radical, in this case, each of the other two substituents represents an alkyl radical, PA0 (b) the sum of their carbon atoms is never inferior to 4. They are useful as anxiolytic and antiagressive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.