Antibiotic 67-121, a polyene antifungal antibiotic produced by Actinoplanes caeruleus
US4223130A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 28, 1978 |
| Grant date | Sep 16, 1980 |
| Priority date | — |
| Expiry date | Sep 28, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/045
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A microorganism of the genus Actinoplanes produces a novel complex of polyene antibiotics herein designated collectively Antibiotic 67-121 (and sometimes referred to as the Antibiotic 67-121 complex). The individual components are designated Antibiotic 67-121A, Antibiotic 67-121B, Antibiotic 67-121C and Antibiotic 67-121D. The individual components have ultraviolet spectra characteristic of heptaenes. Further, they are orally active against a variety of strains of Candida albicans including many clinical isolates thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.