Process for preparing polycyclic heterocycles having a pyran ring
US4223151A · kind A · utility
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Key dates
| Filing date | Feb 3, 1977 |
| Grant date | Sep 16, 1980 |
| Priority date | — |
| Expiry date | Feb 3, 1997 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH10D10/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process applicable to the preparation of a wide variety of novel polycyclic heterocycles having a newly-formed pyran ring is disclosed. According to the process an aromatic nucleus bearing an ethanol group, for example, 3,4-dimethoxyphenethyl alcohol, is condensed with an aldehyde or ketone or a protected aldehyde or ketone, for example, aminoactaldehyde diethyl acetal, in the presence of an acid catalyst to afford the polycyclic heterocycle, for example, 6,7-dimethoxy-1-isochromanmethylamine. The new heterocycles so formed are useful for preparing derivatives having antiinflammatory, antibacterial or antifungal activities.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.