Patent · US Expired

Protein specific polymeric immunomicrospheres

US4224198A · kind A · utility

16Cited by
1References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 1978
Grant dateSep 23, 1980
Priority date
Expiry dateMay 26, 1998

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/827
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Small, round, bio-compatible microspheres capable of covalently bonding proteins and having a uniform diameter below about 3500 A are prepared by substantially instantaneously initiating polymerization of an aqueous emulsion containing no more than 35% total monomer including an acrylic monomer substituted with a covalently bondable group such as hydroxyl, amino or carboxyl and a minor amount of a cross-linking agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.