Antihypertensive 2H-indol-2-ones
US4224333A · kind A · utility
7Cited by
5References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 15, 1979 |
| Grant date | Sep 23, 1980 |
| Priority date | — |
| Expiry date | Mar 15, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel optically active isomers or racemates of 1,3-dihydro-3-{1-[2-(2,3-dihydro-1,4-benzodioxin-2-yl)-2-hydroxyethyl]-pip eridin-4-yl}-2H-indol-2-ones of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, chlorine, bromine, fluorine and alkoxy of 1 to 5 carbon atoms and R.sub.2 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having antihypertensive activity and a novel process and intermediates for their preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.