Process for the in-vitro biosynthesis of hormones, especially insulin

US4225671A · kind A · utility

Assignee

• Battelle Institute e.V. · DE

Inventors

• Herwig Puchinger · Hamburg, DE
• Ulrich Mueller · Hamburg, DE
• Manfred Sernetz · Biebertal, DE

Key dates

• Filing date: Jun 9, 1978
• Grant date: Sep 30, 1980
• Expiry date: Jun 9, 1998

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/813
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Process for the in-vitro biosynthesis of hormones, especially of insulin, by in-vitro conservation or in-vitro propagation of cells from organs and tissues of animal or human origin under suitable cell growth and cell conservation conditions and isolation of the substance formed in a known manner from the culture medium or by processing of the cells. The hormone-producing cells are propagated or conserved in one or more cell culture spaces separated by semipermeable flat membranes of at least one culture medium space.