Diagnostic agents
US4226713A · kind A · utility
Inventor
Key dates
| Filing date | Apr 24, 1978 |
| Grant date | Oct 7, 1980 |
| Priority date | — |
| Expiry date | Apr 24, 1998 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/104165
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Diagnostic agents are described for determining high density lipoprotein cholesterol in body fluids such as serum or plasma. One is an enzymatic reagent for quantitative analysis for cholesterol composed of cholesterol oxidase, cholesterol esterase, peroxidase, 4-amino-antipyrine, a phenol or phenol derivative, a surfactant, such as sodium cholate and a polyglycol of molecular weight from about 190 to 1000, buffered to pH 5.5 to 7.8 in water. The other is a single, stable precipitating agent for lipoproteins in body fluids, comprising a bivalent metal salt of a monobasic acid, such as magnesium chloride and a water-soluble polyanion, such as sodium phosphotungstate in water at pH 5 to 8.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.