7-Substituted aminoacetamido oxadethiacephalosporins
US4226864A · kind A · utility
13Cited by
7References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 22, 1977 |
| Grant date | Oct 7, 1980 |
| Priority date | — |
| Expiry date | Aug 22, 1997 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibacterial 7-substituted aminoacetamido oxadethiacephalosporins of the formula: ##STR1## [wherein R is substituted amino, substituted phenyl, or 5- or 6-membered hetero ring; Ar is aryl; Y is hydrogen or methoxy; Het is 5- or 6-membered aromatic hetero ring; and Z is hydroxy or carboxy protecting group] preparable e.g. by acylation of 7.alpha.-methoxy-7.beta.-amino-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives, are highly active against gram-positive and gram-negative bacteria, especially those resistant to other cephalosporins and penicillins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.