1-Substituted glycopyranosides
US4228274A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 10, 1978 |
| Grant date | Oct 14, 1980 |
| Priority date | — |
| Expiry date | Jul 10, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention disclosed herein relates to novel 1-deoxy-glycopyranosides, preferably 1-deoxy-D-mannopyranosides, having in the 1-position of the pyranoside ring an .omega.-aminoalkylthio, .omega.-aminoalkyloxy or .omega.-aminoalkanoylamino substituent; and to novel processes for preparing these 1-substituted-1-deoxy-glycopyranosides starting with the corresponding tetra-O-acetyl-glycopyranosyl bromide or amine. These .omega.-amino(alkylthio, alkyloxy or alkanoylamino)-1-deoxy-glycopyranosides, and in particular 1-[(6'-aminohexyl)thio or oxy]-1-deoxy-D-mannopyranosides, possess insulin-like activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.