Patent · US Expired

1-Substituted glycopyranosides

US4228274A · kind A · utility

15Cited by
5References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 10, 1978
Grant dateOct 14, 1980
Priority date
Expiry dateJul 10, 1998

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H15/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention disclosed herein relates to novel 1-deoxy-glycopyranosides, preferably 1-deoxy-D-mannopyranosides, having in the 1-position of the pyranoside ring an .omega.-aminoalkylthio, .omega.-aminoalkyloxy or .omega.-aminoalkanoylamino substituent; and to novel processes for preparing these 1-substituted-1-deoxy-glycopyranosides starting with the corresponding tetra-O-acetyl-glycopyranosyl bromide or amine. These .omega.-amino(alkylthio, alkyloxy or alkanoylamino)-1-deoxy-glycopyranosides, and in particular 1-[(6'-aminohexyl)thio or oxy]-1-deoxy-D-mannopyranosides, possess insulin-like activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.