Preparation of blood fraction
US4229435A · kind A · utility
11Cited by
1References
10Claims
0Family size
Inventors
Key dates
| Filing date | Jan 23, 1979 |
| Grant date | Oct 21, 1980 |
| Priority date | — |
| Expiry date | Jan 23, 1999 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/831
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Concentrates of one of the coagulation factors II, V and VIII or a mixture thereof or blood plasma free from one or more of the coagulation factors VII, IX, X, XI and XII can be prepared by adding a reducing substance comprised of dithiothreitol, dithioerythritol, lipoic acid, mercaptoethanol, or a borohydride to blood or plasma, dithiothreitol being preferred. The amount of reducing substance and the period of time for interaction are so adapted to obtain the product desired, whereafter the blood and plasma, respectively, are optionally fractionated in a known manner.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.