Theophylline antigens and antibodies
US4230805A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 11, 1979 |
| Grant date | Oct 28, 1980 |
| Priority date | — |
| Expiry date | Jan 11, 1999 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/806
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Theophylline derivatives are provided for preparing reagents for use in competitive protein binding assays and for use as reagents in competitive protein binding assays. Theophylline is substituted at the 3 position and conjugated to antigens for production of antibodies which specifically recognize theophylline as distinct from structurally similar analogs such as caffeine. Enzyme conjugates are provided which find use for measuring the amount of theophylline in a sample suspected of containing theophylline. A method is provided employing the reagents for the determination of theophylline.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.