1-Oxo-1H-pyrimido[6,1-b]benzthiazole derivatives

US4232024A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Werner Winter · Aachen, DE
• Herman Hindermayr · Mannheim, DE
• Egon Roesch · Mannheim, DE
• Androniki Roesch · Mannheim, DE
• Otto-Henning Wilhelms · Weinheim, DE

Key dates

• Filing date: Feb 26, 1979
• Grant date: Nov 4, 1980
• Expiry date: Feb 26, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Anti-allergy novel 1-oxo-1H-pyrimido[6,1-b]benzthiazole derivatives of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each independently is hydrogen, halogen, hydroxy, nitro, trifluoromethyl, or lower alkyl, alkoxy or alkylthio, or PA1 R.sub.2 and R.sub.3 together are alkylenedioxy, and PA1 X is hydroxy, alkoxy or tetrazolyl-5-amino, or salts thereof, as well as their production by saponification of ##STR2## or tautomers thereof, followed by acidification.