Process for selecting methine dyes which inhibit cell growth

US4232121A · kind A · utility

Assignee

• EASTMAN KODAK COMPANY · US

Inventors

• Paul B. Gilman · Penfield, US
• Robert T. Belly · Webster, US
• Thaddeus D. Koszelak · Rochester, US
• Seymour Zigman · Munich, DE

Key dates

• Filing date: Sep 25, 1978
• Grant date: Nov 4, 1980
• Expiry date: Sep 25, 1998

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/18
• WIPO field: Basic materials chemistry
• WIPO sector: Chemistry

Abstract

Methine dyes which inhibit cell growth are identified by (1) determining the reduction potential of the dye, (2) determining the ability of the dye to sorb to the cells and (3) selecting those dyes which have a reduction potential more negative than about -0.8 volt and which are sorbed to the cells.