Pyrazolyl amino imidazolines as antihypertensive agents
US4234594A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 7, 1979 |
| Grant date | Nov 18, 1980 |
| Priority date | — |
| Expiry date | May 7, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Described is a method of treating hypertensive by administering to mammalian patients compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen, loweralkyl, lowercycloalkyl, aralkyl, aryl, pyridyl, isoquinolyl, phthalazinyl, or aryl substituted by one or more hydrogen, halo, loweralkyl, lowercycloalkyl, haloloweralkyl, haloloweralkyl, aminosulfonyl, nitro, hydroxy, alkoxy, carboxy, alkoxycarbonyl, cycloalkoxy carbonyl, aminocarbonyl, diloweralkylaminocarbonyl or ##STR2## wherein n is 4 or 5. PA0 R.sub.3 is hydrogen, halogen, loweralkyl or aryl, and PA0 R.sub.4 is hydrogen, acyl, amino or loweralkyl, and the pharmaceutically acceptable acid addition salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.