Patent · US Expired

Method and reagent for determining biologically active heparin in plasma

US4234682A · kind A · utility

24Cited by

6References

7Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Knut Bartl · Weilheim in Oberbayern, DE
Helmut Lill · Wielenbach, DE
Joachim Ziegenhorn · Starnberg, DE

Key dates

Filing date	Feb 21, 1979
Grant date	Nov 18, 1980
Priority date	—
Expiry date	Feb 21, 1999

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/143333
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method for determining biologically active heparin comprising adding, in the absence of exogenous antithrombin III, a proteolytic enzyme selected from the group consisting of thrombin and factor Xa and a chromogen substrate for the enzyme to a heparin sample, measuring the dye released from the chromogen substrate and thus determining the amount of heparin present.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.