Tandem quadrupole mass spectrometer for selected ion fragmentation studies and low energy collision induced dissociator therefor
US4234791A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1978 |
| Grant date | Nov 18, 1980 |
| Priority date | — |
| Expiry date | Nov 13, 1998 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/005
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
A tandem quadrupole-based mass spectrometer including a highly efficient intermediate fragmentation stage. The disclosed fragmentation stage employs collision-induced dissociation (CID), in an electrodynamic focus device, which may be a quadrupole operated in a broad band filter mode. The disclosed CID process occurs at low energy (e.g., less than 1 keV, but preferably 2 eV to 100 eV), and is quite different from the high energy (e.g, greater than 1 keV, and typically 3 keV to 10 keV) CID process in prior tandem instruments such as mass-analyzed ion kinetic energy spectrometry (MIKES) systems. The efficiency of the present CID fragmentation is as high as 65%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.