Substituted O-(2-hydroxypropyl)-aldoximes

US4235899A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Ulrich Gebert · Königstein, DE
• Wolfgang Raether

Key dates

• Filing date: Nov 9, 1977
• Grant date: Nov 25, 1980
• Expiry date: Nov 9, 1997

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/95
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of general formula ##STR1## wherein X represents a methine group and Y is an oxygen atom, or X represents a nitrogen atom and Y the group NR.sup.3 in which R.sup.3 represents a radical selected from the group consisting of a hydrogen atom, a methyl, ethyl and hydroxyethyl group; and R.sup.1 and R.sup.2 each represent a radical of the group hydrogen atom, an alkyl and hydroxyalkyl group each containing up to 6 carbon atoms, or an aryl group containing up to 10 carbon atoms; and R.sup.1 and R.sup.2, together with the nitrogen atom to which they are attached, form a 5- to 7-membered saturated ring which contains not more than one further, heterocyclic atom selected from the group consisting of oxygen, sulphur and nitrogen and being unsubstituted or substituted by one of the groups an alkyl and hydroxyalkyl group each containing up to 6 carbon atoms and an aryl group containing up to 10 carbon atoms and physiologically acceptable acid addition salts thereof and a pharmaceutical composition containing them.