2-Methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene and salts thereof, neuroleptic compositions and method of use
US4235916A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 20, 1978 |
| Grant date | Nov 25, 1980 |
| Priority date | — |
| Expiry date | Dec 20, 1998 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to the novel compound 2-methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene of the formula ##STR1## and its non-toxic acid addition salts, which compounds have strong and longlasting neuroleptic properties and, at the same time, a low degree of undesired side effects such as extrapyrimidal side effects. The invention moreover relates to a method for the preparation of said novel compounds, pharmaceutical compositions containing same, which may be administered to animals, including human beings, orally or parentally. Further the invention relates to a method for producing an antipsychotic effect in warmblooded animals by administering to said animals an antipsychotically effective amount of one of said novel compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.