Method of screening for sickle cell disease by detection of porphyrins and porphyrin metabolites in human dentition
US4236526A · kind A · utility
17Cited by
4References
14Claims
0Family size
Inventor
Key dates
| Filing date | Jan 31, 1978 |
| Grant date | Dec 2, 1980 |
| Priority date | — |
| Expiry date | Jan 31, 1998 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61C19/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of screening for sickle cell disease is provided by detecting the presence of porphyrins and porphyrin metabolites in human teeth comprising cleaning the teeth, exposing the cleaned teeth in vivo to a source of light, which has a wavelength known to excite the fluorescent emission spectrum characteristic of porphyrins and porphyrin metabolites and, optimally, which emits a wavelength of about 360 nm, detecting fluorescence, either visually or photographically, and determining the presence of porphyrins or porphyrin metabolites by emission of fluorescence characteristic thereto.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.