Bis(nitrosoureido)-polyol derivatives
US4237273A · kind A · utility
3Cited by
5References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1978 |
| Grant date | Dec 2, 1980 |
| Priority date | — |
| Expiry date | Jul 17, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/28
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to bis(nitrosoureido)-polyol derivatives of general formula I EQU B.sub.1 --A--B.sub.2 (I) wherein PA0 A stands for an open chain polyol comprising 4 to 6 carbon atoms or a six-membered cyclic polyol, and PA0 B.sub.1 and B.sub.2 being attached to two different carbon atoms of the chain A, are identical or different, and stand for a group of general formula II ##STR1## wherein X stands for a halogen atom and PA0 Y and Z stand for a hydrogen atom or a nitroso group, with the restriction, that in B.sub.1 and B.sub.2 Y and Z must be different. The above compounds possess valuable cytostatic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.