Electrodialysis process for the separation of essential amino acids from derivatives thereof
US4238307A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 14, 1979 |
| Grant date | Dec 9, 1980 |
| Priority date | — |
| Expiry date | Feb 14, 1999 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2311/04
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention provides a process for the separation, by electrodialysis, of a mixed aqueous solution, containing an essential amino acid and a derivative of that acid as components therof, wherein one of said components is in charged form and the other of said components is in amphoteric form, into at least two separate product solutions, of acid and derivative respectively, of which at least one product solution contains highly pure product obtained at high quantitative yield, comprising providing an electrodialysis stack, continuously introducing a feed solution containing an essential amino acid and derivative thereof to be separated into feed cells of the stack, adjusting the flow rate and concentration of the solution and the electric current density applied to values adapted to create concentration polarization conditions adjacent to the membranes in the feed cell thereby accumulating a high local concentration of protons upon the surface of the anion exchange membranes, and a high local concentration of hydroxyl ions upon the cation exchange membranes and maintaining the pH of the bulk solution in the feed cells in a range of between 4-8, irrespective of the isoelectric poin…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.