Artificial oligosaccharide antigenic determinants
US4238473A · kind A · utility
46Cited by
4References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 22, 1979 |
| Grant date | Dec 9, 1980 |
| Priority date | — |
| Expiry date | Jan 22, 1999 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/807
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Carbohydrate antigenic determinants containing a glycosidically linked bridging arm are synthesized and coupled to carrier molecules to form artificial antigens, and to solid supports to form immunoadsorbents. Various artificial antigens of the blood group type are prepared and applications shown. Specific examples are given to the synthesis of the Lewis-a, Lewis-b, A, B, and H(O) blood group antigens; to the preparation of antisera to these artificial antigens, to the preparation of immunoadsorbents specific for antibodies to these antigens, and to the detection of such antigens wherever they occur.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.