Penicillins and salts thereof

US4241056A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Bernd Wetzel · Biberach an der Riß, DE
• Wolfgang Reuter
• Eberhard Woitun · Biberach an der Riß, DE
• Roland Maier · Biberach an der Riß, DE
• Uwe Lechner · Biberach an der Riß, DE
• Hanns Goeth · Biberach an der Riß, DE
• Rolf Werner · Ludwigshafen, DE

Key dates

• Filing date: Feb 21, 1979
• Grant date: Dec 23, 1980
• Expiry date: Feb 21, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D499/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein A is phenyl; 4-hydroxy-phenyl; 2- or 3-thienyl; cyclohexyl; cyclohexen-1-yl; cyclohexa-1, 4-dien-1-yl; or 3,4-disubstituted phenyl, where the substituents may be identical to or different from each other and are selected from the group consisting of chlorine, hydroxyl or methoxy; and PA1 R is an aliphatic, cycloaliphatic; aromatic or heterocyclic group of diverse types; and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as their salts are useful as antibiotics.